Comprehensive transcriptomic analysis identifies Lrg1 as a potential therapeutic target for preventing muscle atrophy in cancer cachexia

Cathepsin L as a dual-target to mitigate muscle wasting while enhancing anti-tumor efficacy of anti-PD-L1

Benchmarking of dimensionality reduction methods to capture drug response in transcriptome data

Hepatic miR-93 promotes the pathogenesis of metabolic dysfunction-associated steatotic liver disease by suppressing SIRT1

Butylphthalide identified via Samul-tang-induced transcriptomic signatures improves oocyte quality in aged mice

Transcriptome profiling of aged-mice ovaries administered with individual ingredients of Samul-tang

Paeoniae radix overcomes resistance to EGFR-TKIs via aurora B pathway suppression in lung adenocarcinoma

Integrative transcriptomic analysis identifies emetine as a promising candidate for overcoming acquired resistance to ALK inhibitors in lung cancer

KORE-Map 1.0: Korean medicine Omics Resource Extension Map on transcriptome data of tonifying herbal medicine

Predicting antioxidant activity of compounds based on chemical structure using machine learning methods

Tonic type 2 immunity is a critical tissue checkpoint controlling autoimmunity in the skin

Tumor necrosis factor-inducible gene 6 protein and its derived peptide ameliorate liver fibrosis by repressing CD44 activation in mice with alcohol-related liver disease

Effect of Poria cocos Terpenes: Verifying Modes of Action Using Molecular Docking, Drug-Induced Transcriptomes, and Diffusion Network Analyses

Systematic omics analysis identifies CCR6 as a therapeutic target to overcome cancer resistance to EGFR inhibitors

SIRT1 ISGylation accelerates tumor progression by unleashing SIRT1 from the inactive state to promote its deacetylase activity

Amelioration of Astrocyte-Mediated Neuroinflammation by EI-16004 Confers Neuroprotection in an MPTP-induced Parkinson’s Disease Model

Jakyak-gamcho-tang, a decoction of Paeoniae Radix and Glycyrrhizae Radix et Rhizoma, ameliorates dexamethasone-induced muscle atrophy and muscle dysfunction

Overexpression of interleukin-8 promotes the progression of fatty liver to nonalcoholic steatohepatitis in mice

FSP1 confers ferroptosis resistance in KEAP1 mutant non-small cell lung carcinoma in NRF2-dependent and-independent manner

Integrative Transcriptomic Analysis Reveals Upregulated Apoptotic Signaling in Wound-Healing Pathway in Rat Liver Fibrosis Models

Ginsenoside Rc, an Active Component of Panax ginseng, Alleviates Oxidative Stress-Induced Muscle Atrophy via Improvement of Mitochondrial Biogenesis

TPX2 amplification-driven aberrant mitosis in culture adapted human embryonic stem cells with gain of 20q11. 21

In Silico Discovery of 5′-Modified 7-Deoxy-7-ethynyl-4′-thioadenosine as a HASPIN Inhibitor and Its Synergistic Anticancer Effect with the PLK1 Inhibitor

Epigenetic Activation of Tensin 4 Promotes Gastric Cancer Progression

Liver X receptor controls follicular helper T cell differentiation via repression of TCF-1

TPX2 prompts mitotic survival via the induction of BCL2L1 through YAP1 protein stabilization in human embryonic stem cells

Systematic transcriptome analysis reveals molecular mechanisms and indications of bupleuri radix

Activation of the HSP27-AKT axis contributes to gefitinib resistance in non-small cell lung cancer cells independent of EGFR mutations

Anti-inflammatory and neuroprotective effects of Morin in an MPTP-Induced Parkinson’s Disease Model

Systems pharmacology approaches in herbal medicine research: a brief review

Identification of a novel anticancer mechanism of Paeoniae Radix extracts based on systematic transcriptome analysis

FusionGDB 2.0: fusion gene annotation updates aided by deep learning

BAP1 downregulates NRF2 target genes and exerts anti-tumorigenic effects by deubiquitinating KEAP1 in lung adenocarcinoma

Necrostatin-1 prevents ferroptosis in a RIPK1-and IDO-independent manner in hepatocellular carcinoma

TPX2 Induces Mitotic Survival via BCL2L1 Induction Through YAP1 Protein Stabilization in Human Embryonic Stem Cells

TGFβ promotes YAP‐dependent AXL induction in mesenchymal‐type lung cancer cells

Crosstalk between YAP and TGFβ regulates SERPINE1 expression in mesenchymal lung cancer cells

TRIM24-RIP3 axis perturbation accelerates osteoarthritis pathogenesis

Safe scarless cassette-free selection of genome-edited human pluripotent stem cells using temporary drug resistance

Systematic identification of a nuclear receptor-enriched predictive signature for erastin-induced ferroptosis

Osteoclast-associated receptor blockade prevents articular cartilage destruction via chondrocyte apoptosis regulation

Identification of MYC as an antinecroptotic protein that stifles RIPK1–RIPK3 complex formation

Connectivity map-based drug repositioning of bortezomib to reverse the metastatic effect of GALNT14 in lung cancer

ERK dephosphorylation through MKP1 deacetylation by SIRT1 attenuates RAS-driven tumorigenesis

CSgator: an integrated web platform for compound set analysis

In silico drug repositioning: from large-scale transcriptome data to therapeutics

Structure-activity relationship analysis of YM155 for inducing selective cell death of human pluripotent stem cells

Scarless enriched selection of genome edited human pluripotent stem cells using induced drug resistance

Large-scale pharmacogenomics based drug discovery for ITGB3 dependent chemoresistance in mesenchymal lung cancer

In silico Drug Repositioning of bortezomib to reverse metastatic effect of GALNT14 in lung cancer

Drug repositioning for cancer therapy based on large-scale drug-induced transcriptional signatures

A recurrent inactivating mutation in RHOA GTPase in angioimmunoblastic T cell lymphoma

ChimerDB 2.0—a knowledgebase for fusion genes updated